DISITAMAB VEDOTIN COMBINED WITH PYROTINIB AS SALVAGE TREATMENT IN HER-2-AMPLIFIED TREATMENT REFRACTORY METASTATIC COLORECTAL CANCER: A CASE REPORT

Disitamab vedotin combined with pyrotinib as salvage treatment in Her-2-amplified treatment refractory metastatic colorectal cancer: a case report

BackgroundHuman epidermal growth light pink yeti tumbler factor receptor 2 (HER-2) amplification has been identified in approximately 3% of patients with metastatic colorectal cancer (mCRC).Owing to the lack of established anti-ERBB2 therapeutic approaches, mCRC patients with Her-2 amplification rarely receive targeted treatments.Moreover, conventi

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Detection, quantification and genotyping of Herpes Simplex Virus in cervicovaginal secretions by real-time PCR: a cross sectional survey

Abstract Background Herpes Simplex Virus (HSV) Genital Ulcer Disease (GUD) is an important public health problem, whose interaction with HIV st patricks day teacher gift results in mutually enhancing epidemics.Conventional methods for detecting HSV tend to be slow and insensitive.We designed a rapid PCR-based assay to quantify and type HSV in cervi

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